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Article

Gender specific effect of LIPC C-514T polymorphism on obesity and relationship with plasma lipid levels in Chinese children.

Journal of cellular and molecular medicine - 1 Sept 2015

Wang Hao, Zhang Dandan, Ling Jie, Lu Wenhui, Zhang Shuai, Zhu Yimin, Lai Maode

Abstract excerpt

Hepatic lipase (LIPC) is a key rate-limiting enzyme in lipoprotein catabolism pathways involved in the development of obesity. The C-514T polymorphism in the promoter region is associated with decreased LIPC activity. We performed a case-controlled study (850 obese children and 2119 controls) and evaluated the association between LIPC C-514T polymorphism, obesity and plasma lipid profile in Chinese children and...

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Source

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Identifiers

PMID: 26282880
DOI: 10.1111/jcmm.12663
PMCID: PMC4568933

Genes

LIPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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