Article
Neuropilin-2 and Its Transcript Variants Correlate with Clinical Outcome in Bladder Cancer.
Genes - 9 Apr 2021
Förster Sarah, Givehchi Maryam, Nitschke Katja, Mayr Thomas, Kilian Kerstin, Dutta Samikshan, Datta Kaustubh, Nuhn Philipp, Popovic Zoran, Muders Michael H, Erben Philipp
Abstract excerpt
Urothelial bladder cancer ranks among the 10 most frequently diagnosed cancers worldwide. In our previous study, the transmembrane protein neuropilin-2 (NRP2) emerged as a predictive marker in patients with bladder cancer. NRP2 consists of several splice variants; the most abundant of these, NRP2a and NRP2b, are reported to have different biological functions in lung cancer progression. For other cancer types,...
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