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Article

Nationwide evaluation of mutation-tailored treatment of gastrointestinal stromal tumors in daily clinical practice.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Sept 2021

Steeghs Elisabeth M P, Gelderblom Hans, Ho Vincent K Y, Voorham Quirinus J M, Willems Stefan M, Grünberg Katrien, Ligtenberg Marjolijn J L

Abstract excerpt

BACKGROUND: Molecular analysis of KIT and PDGFRA is critical for tyrosine kinase inhibitor treatment selection of gastrointestinal stromal tumors (GISTs) and hence recommended by international guidelines. We performed a nationwide study into the application of predictive mutation testing in GIST patients and its impact on targeted treatment decisions in clinical practice. METHODS: Real-world clinical and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33909171
DOI: 10.1007/s10120-021-01190-9
PMCID: PMC8338807

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