Transformation to diffuse large B-cell lymphoma with germinal center B-cell like subtype and discordant light chain expression in a patient with Waldenström macroglobulinemia/lymphoplasmacytic lymphoma.

doi:10.1007/s12185-021-03157-z

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Article

Transformation to diffuse large B-cell lymphoma with germinal center B-cell like subtype and discordant light chain expression in a patient with Waldenström macroglobulinemia/lymphoplasmacytic lymphoma.

International journal of hematology - 1 Sept 2021

Kobayashi Hiroki, Asada Noboru, Egusa Yuria, Ikeda Tomoka, Sakamoto Misa, Abe Masaya, Ennishi Daisuke, Sakata Masahiro, Takaki Akinobu, Kawahara Soichiro, Meguri Yusuke, Nishimori Hisakazu, Fujii Nobuharu, Matsuoka Ken-Ichi, Sato Yasuharu, Yoshino Tadashi, Maeda Yoshinobu

Abstract excerpt

Waldenström macroglobulinemia (WM)/lymphoplasmacytic lymphoma (LPL) is a rare indolent B-cell neoplasm, and a gain-of-function mutation in the myeloid differentiation primary response 88 (MYD88), L265P, is a commonly recurring mutation in patients with WM/LPL. Histological transformation of WM/LPL to an aggressive lymphoma such as diffuse large B-cell lymphoma (DLBCL) is rare, and transformed DLBCL has a worse...

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PMID: 33907976
DOI: 10.1007/s12185-021-03157-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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