Article
The Association of Aging-Related Polymorphisms with Susceptibility to Lung Cancer: A Case-Control Study in a Japanese Population.
Asian Pacific journal of cancer prevention : APJCP - 1 Apr 2021
Furuie Hironobu, Arimura-Omori Masako, Hamada Naoki, Yanagihara Toyoshi, Kiyohara Chikako
Abstract excerpt
BACKGROUND: Telomere length is associated with cancer as well as aging. Telomerase reverse transcriptase (TERT), telomere RNA component (TERC) and oligonucleotide/oligosaccharide-binding fold containing 1 (OBFC1) are known to be involved in telomere length regulation. The tumor suppressor p53 (TP53), which has been shown to interact with tumor protein p53-binding protein 1 (TP53BP1), is implicated in the...
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