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Monitoring levels of vimentin-positive circulating cancer stem cells and tumor cells in patients with advanced EGFR-mutated non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Jun 2021

Hsu Chia-Lin, Tsai Tzu-Hsiu, Huang Chun-Kai, Yang Ching-Yao, Liao Wei-Yu, Ho Chao-Chi, Ruan Sheng-Yuan, Chen Kuan-Yu, Shih Jin-Yuan, Yang Pan-Chyr

Abstract excerpt

OBJECTIVES: Circulating tumor cells (CTCs) are associated with tumor spread, whereas cancer stem cells may be related to drug resistance. However, few studies have analyzed the levels of circulating cancer stem cells (CCSCs) and CTCs in patients with advanced non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: Treatment-naïve patients with EGFR-mutated NSCLC who received epidermal growth factor receptor...

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PMID: 33894494
DOI: 10.1016/j.lungcan.2021.04.014

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