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Article

MiR-139 Induces an Interferon-β Response in Prostate Cancer Cells by Binding to RIG-1

1 Jan 2021

Abstract excerpt

BACKGROUND: We previously identified a panel of five miRNAs associated with prostate cancer recurrence and metastasis. Expression of one of the down-regulated miRNAs, miR-139-5p, was significantly associated with a lower incidence of biochemical recurrence and metastasis. Transcriptome profiling of miR-139-expressing prostate cancer cells revealed up-regulation of genes involved in interferon (IFN) stimulation....

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Identifiers

PMID: 33893074
DOI: 10.21873/cgp.20252

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