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MicroRNA‐205–directed transcriptional activation of tumor suppressor genes in prostate cancer

24 Aug 2010

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are small noncoding RNAs that regulate the expression of approximately 60% of all human genes. They play important roles in numerous cellular processes, including development, proliferation, and apoptosis. Currently, it is believed that miRNAs elicit their effect by silencing the expression of target genes. In this study, the authors demonstrated that miRNA-205 (miR-205) induced the...

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PMID: 20737563
DOI: 10.1002/cncr.25488

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