Article
Enrichment and enumeration of circulating tumor cells by efficient depletion of leukocyte fractions.
Clinical chemistry and laboratory medicine - 1 Feb 2014
Wu Shiyang, Liu Zhiming, Liu Suyan, Lin Li, Yang Weiwei, Xu Jiasen
Abstract excerpt
BACKGROUND: Enumeration and characterization of circulating tumor cells (CTCs) can provide information on patient prognosis and treatment efficacy. However, CTCs are rare, making their isolation a major technological challenge. We developed a technique for enrichment, and subsequent characterization of CTCs based on efficient depletion of human leukocytes. METHODS: The technique (CanPatrolTM CTC enrichment) we...
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