Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Engineering spatial-organized cardiac organoids for developmental toxicity testing

22 Apr 2021

Abstract excerpt

Emerging technologies in stem cell engineering have produced sophisticated organoid platforms by controlling stem cell fate via biomaterial instructive cues. By micropatterning and differentiating human induced pluripotent stem cells (hiPSCs), we have engineered spatially organized cardiac organoids with contracting cardiomyocytes in the center surrounded by stromal cells distributed along the pattern perimeter....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3D Printing in Biomedical Research
Share to Pluripotent Stem Cells Research
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33891865
DOI: 10.1016/j.stemcr.2021.03.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Engineering spatial-organized cardiac organoids for developmental toxicity testingPMID 33891865Read ↗

Self-organizing human cardiac microchambers mediated by geometric confinementSemantic proximity Read ↗

Self-assembling human heart organoids for the modeling of cardiac development and congenital heart diseaseSemantic proximity Read ↗

In vitro models of the human heartSemantic proximity Read ↗

Industrialization of three-dimensional hiPSC-cardiac microtissues for high-throughput cardiac safety and drug discovery screeningSemantic proximity Read ↗

Recent Advances in Generation of In Vitro Cardiac OrganoidsSemantic proximity Read ↗

Engineered platforms for mimicking cardiac development and drug screeningSemantic proximity Read ↗

Engineering aligned human cardiac muscle using developmentally inspired fibronectin micropatternsSemantic proximity Read ↗

A patterned human primitive heart organoid model generated by pluripotent stem cell self-organizationSemantic proximity Read ↗

Inspiration from heart development: Biomimetic development of functional human cardiac organoids.Semantic proximity Read ↗

Human Cardiac Organoids for Modeling Genetic Cardiomyopathy.Semantic proximity Read ↗

Generation of spatial-patterned early-developing cardiac organoids using human pluripotent stem cellsSemantic proximity Read ↗

Size-Modulated Mesoderm-Endoderm Divergence and Myocardial Cavitation in Micropatterned CardioidsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.