Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect ofACE1polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium

25 Feb 2021

Abstract excerpt

Increased protein levels of ACE2 in alveolar epithelium of subjects who are homozygous for the ACE1 insertion of rs1799752 might facilitate host cell entry of #SARSCoV2 and explain the higher prevalence of #COVID19 in certain regionshttps://bit.ly/3k6aAE8

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to Influenza Virus Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to SARS-CoV-2 and COVID-19 Research

Source

Identifiers

PMID: 33889638
DOI: 10.1183/23120541.00940-2020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect ofACE1polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epitheliumPMID 33889638Read ↗

A Closer Look at ACE2 Signaling Pathway and Processing during COVID-19 Infection: Identifying Possible TargetsSemantic proximity Read ↗

ACE2 and TMPRSS2 polymorphisms in various diseases with special reference to its impact on COVID-19 disease.Semantic proximity Read ↗

A survey of genetic variants in SARS-CoV-2 interacting domains of ACE2, TMPRSS2 and TLR3/7/8 across populationsSemantic proximity Read ↗

Differential expression in humans of the viral entry receptor ACE2 compared with the short deltaACE2 isoform lacking SARS-CoV-2 binding sitesSemantic proximity Read ↗

COVID-19 infections are also affected by human ACE1 D/I polymorphismSemantic proximity Read ↗

Comprehensive in silico identification of impacts of ACE2 SNPs on COVID-19 susceptibility in different populationsSemantic proximity Read ↗

Epigenetic mechanisms and host factors impact ACE2 gene expression: Implications in COVID-19 susceptibilitySemantic proximity Read ↗

SARS-CoV-2 susceptibility and <i>ACE2</i> gene variations within diverse ethnic backgroundsSemantic proximity Read ↗

Interaction of the spike protein RBD from SARS-CoV-2 with ACE2: Similarity with SARS-CoV, hot-spot analysis and effect of the receptor polymorphismSemantic proximity Read ↗

A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infectionSemantic proximity Read ↗

Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.Semantic proximity Read ↗

SARS-CoV-2 Susceptibility and ACE2 Gene Variations Within Diverse Ethnic BackgroundsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.