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Article

Predicting rifampicin resistance mutations in bacterial RNA polymerase subunit beta based on majority consensus.

BMC bioinformatics - 22 Apr 2021

Ning Qing, Wang Dali, Cheng Fei, Zhong Yuheng, Ding Qi, You Jing

Abstract excerpt

BACKGROUND: Mutations in an enzyme target are one of the most common mechanisms whereby antibiotic resistance arises. Identification of the resistance mutations in bacteria is essential for understanding the structural basis of antibiotic resistance and design of new drugs. However, the traditionally used experimental approaches to identify resistance mutations were usually labor-intensive and costly. RESULTS: We...

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Identifiers

PMID: 33888055
DOI: 10.1186/s12859-021-04137-0
PMCID: PMC8063314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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