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Deletion mutation within the goat PPP3CA gene identified by GWAS significantly affects litter size.

Reproduction, fertility, and development - 1 May 2021

Bai Yangyang, Li Jie, Zhu Haijing, Liu Jinwang, Dong Shuwei, Li Longping, Qu Lei, Chen Hong, Song Xiaoyue, Lan Xianyong

Abstract excerpt

The protein phosphatase 3 catalytic subunit α (PPP3CA) gene is a high reproduction traits candidate gene for goats as revealed by a genome-wide association study. The aim of this work was to explore the genetic variations of the goat PPP3CA as well as to evaluate the genetic effects on litter size. Three novel insertions/deletions (indels) within the goat PPP3CA were found and their minor allelic frequencies...

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Identifiers

PMID: 33883061
DOI: 10.1071/RD20337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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