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Article

Cellular Mn/Zn Ratio Influences Phosphoglucomutase Activity and Capsule Production in Streptococcus pneumoniae D39.

Journal of bacteriology - 8 Jun 2021

McFarland Averi L, Bhattarai Nabin, Joseph Merrin, Winkler Malcolm E, Martin Julia E

Abstract excerpt

Capsular polysaccharide (CPS) is a major virulence determinant for many human-pathogenic bacteria. Although the essential functional roles for CPS in bacterial virulence have been established, knowledge of how CPS production is regulated remains limited. Streptococcus pneumoniae (pneumococcus) CPS expression levels and overall thickness change in response to available oxygen and carbohydrate. These nutrients in...

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Identifiers

PMID: 33875543
DOI: 10.1128/JB.00602-20
PMCID: PMC8316032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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