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Article

Association of Isocitrate Dehydrogenase (IDH) Status With Edema to Tumor Ratio and Its Correlation With Immune Infiltration in Glioblastoma.

Frontiers in immunology - 1 Jan 2021

Dubinski Daniel, Won Sae-Yeon, Rauch Maximilian, Behmanesh Bedjan, Ngassam Lionel D C, Baumgarten Peter, Senft Christian, Harter Patrick N, Bernstock Joshua D, Freiman Thomas M, Seifert Volker, Gessler Florian

Abstract excerpt

Purpose: The extent of preoperative peritumoral edema in glioblastoma (GBM) has been negatively correlated with patient outcome. As several ongoing studies are investigating T-cell based immunotherapy in GBM, we conducted this study to assess whether peritumoral edema with potentially increased intracranial pressure, disrupted tissue homeostasis and reduced local blood flow has influence on immune infiltration...

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Source

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Identifiers

PMID: 33868245
DOI: 10.3389/fimmu.2021.627650
PMCID: PMC8044904

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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