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Article

Accelerated Brain Aging in Mild Traumatic Brain Injury: Longitudinal Pattern Recognition with White Matter Integrity.

Journal of neurotrauma - 15 Sept 2021

Gan Shuoqiu, Shi Wen, Wang Shan, Sun Yingxiang, Yin Bo, Bai Guanghui, Jia Xiaoyan, Sun Chuanzhu, Niu Xuan, Wang Zhuonan, Jiang Xiaofan, Liu Jun, Zhang Ming, Bai Lijun

Abstract excerpt

Mild traumatic brain injury (mTBI) initiating long-term effects on white matter integrity resembles brain-aging changes, implying an aging process accelerated by mTBI. This longitudinal study aims to investigate the mTBI-induced acceleration of the brain-aging process by developing a neuroimaging model to predict brain age. The brain-age prediction model was defined using relevance vector regression based on...

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PMID: 33863259
DOI: 10.1089/neu.2020.7551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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