Article
Revisiting the role of MRGPRX2 on hypersensitivity reactions to neuromuscular blocking drugs.
Current opinion in immunology - 1 Oct 2021
Ali Hydar
Abstract excerpt
Anaphylaxis is caused by a variety of triggers including Food and Drug Administration (FDA)-approved antibiotics, contrast media and neuromuscular blocking drugs (NMBDs). Traditionally, drug-induced anaphylaxis was thought to result mainly from IgE-mediated histamine release from mast cells. Recently, a G protein-coupled receptor known as MRGPRX2 has been identified and shown to be highly expressed on human skin...
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