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Article

Distribution of naturally -occurring NS5B resistance-associated substitutions in Egyptian patients with chronic Hepatitis C.

PloS one - 1 Jan 2021

Ahmed Hala Rady, Waly Nancy G F M, Abd El-Baky Rehab Mahmoud, Yahia Ramadan, Hetta Helal F, Elsayed Amr M, Ibrahem Reham Ali

Abstract excerpt

BACKGROUND: NS5B polymerase inhibitors represent the cornerstone of the present treatment of Hepatitis C virus infection (HCV). Naturally occurring substitution mutations to NS5B inhibitors have been recorded. The current study intended to demonstrate possible natural direct acting antiviral (DAA)-mutations of the HCV NS5B region in HCV patients in Minia governorate, Egypt. METHODS: Samples were collected from 27...

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Share to Antiviral Agents
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hepatitis C, Chronic

Share to Immunity, Innate

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Share to Viral Nonstructural Proteins

Source

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Identifiers

PMID: 33857212
DOI: 10.1371/journal.pone.0249770
PMCID: PMC8049381

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