Article
Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil.
Science (New York, N.Y.) - 21 May 2021
Faria Nuno R, Mellan Thomas A, Whittaker Charles, Claro Ingra M, Candido Darlan da S, Mishra Swapnil, Crispim Myuki A E, Sales Flavia C S, Hawryluk Iwona, McCrone John T, Hulswit Ruben J G, Franco Lucas A M, Ramundo Mariana S, de Jesus Jaqueline G, Andrade Pamela S, Coletti Thais M, Ferreira Giulia M, Silva Camila A M, Manuli Erika R, Pereira Rafael H M, Peixoto Pedro S, Kraemer Moritz U G, Gaburo Nelson, Camilo Cecilia da C, Hoeltgebaum Henrique, Souza William M, Rocha Esmenia C, de Souza Leandro M, de Pinho Mariana C, Araujo Leonardo J T, Malta Frederico S V, de Lima Aline B, Silva Joice do P, Zauli Danielle A G, Ferreira Alessandro C de S, Schnekenberg Ricardo P, Laydon Daniel J, Walker Patrick G T, Schlüter Hannah M, Dos Santos Ana L P, Vidal Maria S, Del Caro Valentina S, Filho Rosinaldo M F, Dos Santos Helem M, Aguiar Renato S, Proença-Modena José L, Nelson Bruce, Hay James A, Monod Mélodie, Miscouridou Xenia, Coupland Helen, Sonabend Raphael, Vollmer Michaela, Gandy Axel, Prete Carlos A, Nascimento Vitor H, Suchard Marc A, Bowden Thomas A, Pond Sergei L K, Wu Chieh-Hsi, Ratmann Oliver, Ferguson Neil M, Dye Christopher, Loman Nick J, Lemey Philippe, Rambaut Andrew, Fraiji Nelson A, Carvalho Maria do P S S, Pybus Oliver G, Flaxman Seth, Bhatt Samir, Sabino Ester C
Abstract excerpt
Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Manaus, Brazil, resurged in late 2020 despite previously high levels of infection. Genome sequencing of viruses sampled in Manaus between November 2020 and January 2021 revealed the emergence and circulation of a novel SARS-CoV-2 variant of concern. Lineage P.1 acquired 17 mutations, including a trio in the spike protein (K417T,...
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