Comprehensive tumor molecular profile analysis in clinical practice.

doi:10.1186/s12920-021-00952-9

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Article

Comprehensive tumor molecular profile analysis in clinical practice.

BMC medical genomics - 14 Apr 2021

Özdoğan Mustafa, Papadopoulou Eirini, Tsoulos Nikolaos, Tsantikidi Aikaterini, Mariatou Vasiliki-Metaxa, Tsaousis Georgios, Kapeni Evgenia, Bourkoula Evgenia, Fotiou Dimitrios, Kapetsis Georgios, Boukovinas Ioannis, Touroutoglou Nikolaos, Fassas Athanasios, Adamidis Achilleas, Kosmidis Paraskevas, Trafalis Dimitrios, Galani Eleni, Lypas George, Orhan Bülent, Tansan Sualp, Özatlı Tahsin, Kırca Onder, Çakır Okan, Nasioulas George

Abstract excerpt

BACKGROUND: Tumor molecular profile analysis by Next Generation Sequencing technology is currently widely applied in clinical practice and has enabled the detection of predictive biomarkers of response to targeted treatment. In parallel with targeted therapies, immunotherapies are also evolving, revolutionizing cancer therapy, with Programmed Death-ligand 1 (PD-L1), Microsatellite instability (MSI), and Tumor...

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Identifiers

PMID: 33853586
DOI: 10.1186/s12920-021-00952-9
PMCID: PMC8045191

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