Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The white matter is a pro-differentiative niche for glioblastoma

12 Apr 2021

Abstract excerpt

Glioblastomas are hierarchically organised tumours driven by glioma stem cells that retain partial differentiation potential. Glioma stem cells are maintained in specialised microenvironments, but whether, or how, they undergo lineage progression outside of these niches remains unclear. Here we identify the white matter as a differentiative niche for glioblastomas with oligodendrocyte lineage competency. Tumour...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caveolin-1 and cellular processes
Share to Glioma Diagnosis and Treatment
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33846316
DOI: 10.1038/s41467-021-22225-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The white matter is a pro-differentiative niche for glioblastomaPMID 33846316Read ↗

Invasion of white matter tracts by glioma stem cells is regulated by a NOTCH1–SOX2 positive-feedback loopSemantic proximity Read ↗

Regional Development of Glioblastoma: The Anatomical Conundrum of Cancer Biology and Its Surgical ImplicationSemantic proximity Read ↗

Neurodevelopmental hijacking of oligodendrocyte lineage programs drives glioblastoma infiltrationSemantic proximity Read ↗

Glioma Revisited: From Neurogenesis and Cancer Stem Cells to the Epigenetic Regulation of the NicheSemantic proximity Read ↗

Hitting a Moving Target: Glioma Stem Cells Demand New Approaches in Glioblastoma TherapySemantic proximity Read ↗

Oligodendroglial-specific Transcriptional Factor SOX10 is Ubiquitously Expressed in Human GliomasSemantic proximity Read ↗

The Impact of the Tumor Microenvironment on the Properties of Glioma Stem-Like CellsSemantic proximity Read ↗

Neuronal and tumourigenic boundaries of glioblastoma plasticitySemantic proximity Read ↗

Targeting glioma stem cells: A novel framework for brain tumorsSemantic proximity Read ↗

The cellular origin for malignant glioma and prospects for clinical advancements.Semantic proximity Read ↗

The Subventricular Zone in Glioblastoma: Genesis, Maintenance, and ModelingSemantic proximity Read ↗

SOX transcription factors and glioma stem cells: Choosing between stemness and differentiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.