Article
Adiposity and Interstitial Lung Abnormalities in Community-Dwelling Adults: The MESA Cohort Study.
Chest - 1 Aug 2021
Anderson Michaela R, Kim John S, Allison Matthew, Giles Jon T, Hoffman Eric A, Ding Jingzhong, Barr R Graham, Podolanczuk Anna
Abstract excerpt
BACKGROUND: Obesity is associated with restrictive ventilatory defects and a faster rate of decline in FVC. This association is not exclusively mediated by mechanical factors and may reflect direct pulmonary injury by adipose-derived mediators. RESEARCH QUESTION: Is adipose tissue involved in the pathogenesis of interstitial lung disease (ILD)? STUDY DESIGN AND METHODS: We evaluated the association of CT measures...
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