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Swine Host Protein Coiled-Coil Domain-Containing 115 (CCDC115) Interacts with Classical Swine Fever Virus Structural Glycoprotein E2 during Virus Replication.

Viruses - 31 Mar 2020

Vuono Elizabeth A, Ramirez-Medina Elizabeth, Berggren Keith, Rai Ayushi, Pruitt Sarah, Silva Ediane, Velazquez-Salinas Lauro, Gladue Douglas P, Borca Manuel V

Abstract excerpt

Interactions between the major structural glycoprotein E2 of classical swine fever virus (CSFV) with host proteins have been identified as important factors affecting virus replication and virulence. Previously, using the yeast two-hybrid system, we identified swine host proteins specifically interacting with CSFV E2. In this report, we use a proximity ligation assay to demonstrate that swine host protein CCDC115...

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Source

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Identifiers

PMID: 32244508
DOI: 10.3390/v12040388
PMCID: PMC7232474

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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