Article
Mendelian randomization as an approach to assess causal effects of inflammatory bowel disease on atrial fibrillation.
Aging - 6 Apr 2021
Chen LaiTe, Fu GuoSheng, Jiang ChenYang
Abstract excerpt
BACKGROUND: Despite growing evidence indicating that patients with inflammatory bowel disease (IBD) have an increased risk of atrial fibrillation (AF), owing to the potential biases of confounding effects and reverse causation, the specific relationship between IBD and AF remains controversial. The aim of this study is to determine whether there is a causal effect of IBD on AF. METHODS: A two-sample Mendelian...
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