Article
Rheumatoid arthritis and inflammatory bowel disease: A bidirectional two-sample Mendelian randomization study.
Seminars in arthritis and rheumatism - 1 Aug 2022
Meisinger Christa, Freuer Dennis
Abstract excerpt
OBJECTIVES: An association between arthritis and inflammatory bowel disease (IBD) was found in observational studies. However, neither the direction nor the cause-effect chain is clear. METHODS: A two-sample Mendelian randomization study was carried out to investigate whether rheumatoid arthritis is causally related to IBD and vice versa. Independent genetic instruments from the largest available genome-wide...
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