Article
Mendelian randomization study finds no causal link between inflammatory bowel disease and cirrhosis.
Medicine - 6 Mar 2026
An Jiawei, Zhu Mingyan, Fu Yangsuolang, Gao Kai, Xie Huien, Ding Haoxiang, Guo Chengfeng, Zeng Fuhao, Xiong Yicheng
Abstract excerpt
While some observational research has pointed to a connection between inflammatory bowel disease and increased cirrhosis risk, it has been difficult to determine if this is a genuine cause-and-effect relationship. The challenge lies in separating actual causation from confounding factors that might influence both conditions. In this study, we turned to Mendelian randomization (MR) - a method that uses genetic...
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