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The Effects of Anti-retroviral Therapy on Epigenetic Age Acceleration Observed in HIV-1-infected Adults

22 Oct 2020

Abstract excerpt

Background: HIV-1 infection is associated with acceleration of age-related methylation patterns in peripheral blood and brain of infected individuals although the relative contributions of HIV-1 infection versus its treatment to the observed accelerations in biological aging have not yet been investigated.Methods: In this longitudinal study of the effects of antiretroviral therapy (ART) on epigenetic aging...

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PMID: 33501399
DOI: 10.20411/pai.v5i1.376

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