Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Senescence in tissue samples of humans with age-related diseases: A systematic review.

Ageing research reviews - 1 Jul 2021

Tuttle Camilla S L, Luesken Suzanne W M, Waaijer Mariette E C, Maier Andrea B

Abstract excerpt

BACKGROUND: Higher numbers of senescent cells have been implicated in age-related disease pathologies. However, whether different diseases have different senescent phenotypes is unknown. Here we provide a systematic overview of the current available evidence of senescent cells in age-related diseases pathologies in humans and the markers currently used to detect senescence levels in humans. METHODS: PubMed, Web...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Biomarkers
Share to Cellular Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p16

Share to Phenotype

Source

Identifiers

PMID: 33819674
DOI: 10.1016/j.arr.2021.101334

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Senescence in tissue samples of humans with age-related diseases: A systematic review.PMID 33819674Read ↗

Emerging insights in senescence: pathways from preclinical models to therapeutic innovationsSemantic proximity Read ↗

Hallmarks and mechanisms of cellular senescence in aging and diseaseSemantic proximity Read ↗

Recent advances in biomarkers for senescence: Bridging basic research to clinicSemantic proximity Read ↗

Impact of Senescent Cell Subtypes on Tissue Dysfunction and Repair: Importance and Research QuestionsSemantic proximity Read ↗

Senescent Cells: Emerging Targets for Human Aging and Age-Related Diseases.Semantic proximity Read ↗

Senescent cells as promising targets to tackle age-related diseasesSemantic proximity Read ↗

Senopathies-Diseases Associated with Cellular Senescence.Semantic proximity Read ↗

Cellular Senescence and Ageing: Mechanisms and InterventionsSemantic proximity Read ↗

Biomarkers of Cellular Senescence and Aging: Current State‐of‐the‐Art, Challenges and Future PerspectivesSemantic proximity Read ↗

Hallmarks of cellular senescence: biology, mechanisms, regulationsSemantic proximity Read ↗

Cellular senescence in cardiac diseasesSemantic proximity Read ↗

A guide to assessing cellular senescence in vitro and in vivoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.