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Epigenetic clock and methylation study of oocytes from a bovine model of reproductive aging

2 Apr 2021

Abstract excerpt

Cattle are an attractive animal model of fertility in women due to their high degree of similarity relative to follicle selection, embryo cleavage, blastocyst formation, and gestation length. To facilitate future studies of the epigenetic underpinnings of aging effects in the female reproductive axis, several DNA methylation-based biomarkers of aging (epigenetic clocks) for bovine oocytes are presented. One such...

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PMID: 33797841
DOI: 10.1111/acel.13349

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