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The Hygiene Hypothesis in the Age of the Microbiome

1 Nov 2017

Abstract excerpt

The original version of the hygiene hypothesis suggested that infections transmitted early in life by "unhygienic contact" prevented allergies. Examples were endemic fecal-oral infections by viral, bacterial, or protozoic pathogens, such as hepatitis A virus, Helicobacter pylori, or Toxoplasma gondii. Later, this concept also included microorganisms beyond pathogens, such as commensals and symbionts, and the...

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PMID: 29161087
DOI: 10.1513/annalsats.201702-139aw

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