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Article

Metabolic control of histone demethylase activity involved in plant response to high temperature.

Plant physiology - 23 Apr 2021

Cui Xiaoyun, Zheng Yu, Lu Yue, Issakidis-Bourguet Emmanuelle, Zhou Dao-Xiu

Abstract excerpt

Jumonji C (JmjC) domain proteins are histone lysine demethylases that require ferrous iron and alpha-ketoglutarate (or α-KG) as cofactors in the oxidative demethylation reaction. In plants, α-KG is produced by isocitrate dehydrogenases (ICDHs) in different metabolic pathways. It remains unclear whether fluctuation of α-KG levels affects JmjC demethylase activity and epigenetic regulation of plant gene expression....

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Identifiers

PMID: 33793949
DOI: 10.1093/plphys/kiab020
PMCID: PMC8133595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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