Article
HLA-B Allele, Genotype, and Haplotype Frequencies in a Group of Healthy Individuals in Colombia.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases - 1 Sept 2021
Romero-Sánchez Consuelo, Hernández Natalia, Chila-Moreno Lorena, Jiménez Karen, Padilla Diana, Bello-Gualtero Juan Manuel, Bautista-Molano Wilson
Abstract excerpt
BACKGROUND: The sequencing of alleles of the HLA-B, a human leukocyte antigen (HLA) class I gene, was established as the most polymorphic of chromosome 6 and of the entire human genome. In this locus, the HLA-B*27 allele is highly polymorphic and has clinical relevance. Literature about the subtypes and singular frequency of these alleles in Colombia's healthy population is scarce. OBJECTIVE: The aim of this...
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