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DNA methylation architecture of the ACE2 gene in nasal cells of children

29 Mar 2021

Abstract excerpt

Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has led to the global coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV-2 enters cells via angiotensin-Converting Enzyme 2 (ACE2) receptors, highly expressed in nasal epithelium with parallel high infectivity. 1,2 The nasal epigenome is in direct contact with the environment and could explain COVID-19 disparities by reflecting social and...

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PMID: 33782449
DOI: 10.1038/s41598-021-86494-7

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