Article
Detection of altered methylation of MB-COMT promotor and DRD2 gene in cannabinoid or synthetic cannabinoid use disorder regarding gene variants and clinical parameters.
Journal of addictive diseases - 1 Jan 2000
Oyaci Yasemin, Aytac Hasan Mervan, Pasin Ozge, Cetinay Aydin Pinar, Pehlivan Sacide
Abstract excerpt
This study aims to investigate the association between cannabinoid use disorder (CUD) or synthetic cannabinoid use disorder (SCUD) and methylation status of MB-COMT (membrane-bound catechol-O-methyltransferase) promotor or DRD2 gene considering gene variants and clinical parameters. Based on the DSM-5 criteria, 218 CUD/SCUD patients' diagnoses were confirmed with a positive urine test, and a control group...
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