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RNA-Seq analysis reveals critical transcriptome changes caused by sodium butyrate in DN mouse models

29 Mar 2021

Abstract excerpt

Diabetic nephropathy (DN)-a common complication of diabetes-is the primary cause of end-stage renal disease. Sodium butyrate (NaB) is a short-chain fatty acid (SCFA) that is a metabolic product of intestinal bacterium, and its protective effect on the kidney has been reported in cases of DN. However, its underlying mechanism remains unclear. The aim of the present study was to investigate the effect of NaB on...

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PMID: 33779731
DOI: 10.1042/bsr20203005

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