Article
Comparison of multivariate linear regression and a machine learning algorithm developed for prediction of precision warfarin dosing in a Korean population.
Journal of thrombosis and haemostasis : JTH - 1 Jul 2021
Nguyen Van Lam, Nguyen Hoang Dat, Cho Yong-Soon, Kim Ho-Sook, Han Il-Yong, Kim Dae-Kyeong, Ahn Sangzin, Shin Jae-Gook
Abstract excerpt
BACKGROUND: Personalized warfarin dosing is influenced by various factors including genetic and non-genetic factors. Multiple linear regression (LR) is known as a conventional method to develop predictive models. Recently, machine learning approaches have been extensively implemented for warfarin dosing due to the hypothesis of non-linear association between covariates and stable warfarin dose. OBJECTIVE: To...
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