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Article

Molecular characterization of interactions between the D614G variant of SARS-CoV-2 S-protein and neutralizing antibodies: A computational approach.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2021

Kwarteng Alexander, Asiedu Ebenezer, Sylverken Augustina Angelina, Larbi Amma, Sakyi Samuel Asamoah, Asiedu Samuel Opoku

Abstract excerpt

The D614G variant of SARS-CoV-2 S-protein emerged in early 2020 and quickly became the dominant circulating strain in Europe and its environs. The variant was characterized by the higher viral load, which is not associated with disease severity, higher incorporation into the virion, and high cell entry via ACE-2 and TMPRSS2. Previous strains of the coronavirus and the current SARS-CoV-2 have demonstrated the...

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Share to Angiotensin-Converting Enzyme 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Molecular Dynamics Simulation

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Share to Receptors, Virus

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Share to Spike Glycoprotein, Coronavirus

Source

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Identifiers

PMID: 33774178
DOI: 10.1016/j.meegid.2021.104815
PMCID: PMC7987576

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