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Article

Runs of homozygosity are associated with staging of periodontitis in isolated populations.

Human molecular genetics - 9 Jun 2021

Mezzavilla Massimo, Navarra Chiara Ottavia, Di Lenarda Roberto, Gasparini Paolo, Bevilacqua Lorenzo, Robino Antonietta

Abstract excerpt

Periodontitis is a common inflammatory disease characterized by a complex etiology, which is the result of a combination of genetic and environmental factors. Genetic variants linked to the periodontitis disease were already investigated, however, little was known regarding the severity of this disease. Recently, long runs of homozygosity (ROH) were associated with several multifactorial diseases. Therefore, in...

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Identifiers

PMID: 33772543
DOI: 10.1093/hmg/ddab085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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