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Article

Mesonephric and mesonephric-like carcinomas of the female genital tract: molecular characterization including cases with mixed histology and matched metastases.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2021

da Silva Edaise M, Fix Daniel J, Sebastiao Ana Paula Martins, Selenica Pier, Ferrando Lorenzo, Kim Sarah H, Stylianou Anthe, Da Cruz Paula Arnaud, Pareja Fresia, Smith Evan S, Zehir Ahmet, Konner Jason A, Cadoo Karen, Reis-Filho Jorge S, Abu-Rustum Nadeem R, Mueller Jennifer J, Weigelt Britta, Park Kay J

Abstract excerpt

Mesonephric carcinoma of the cervix is a rare tumor derived from Wolffian remnants. Mesonephric-like carcinomas of the ovary and endometrium, while morphologically similar, do not have obvious Wolffian derivation. Here, we sought to characterize the repertoire of genetic alterations in primary mesonephric and mesonephric-like carcinomas, in the distinct histologic components of mixed cases, as well as in matched...

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PMID: 33772212
DOI: 10.1038/s41379-021-00799-6
PMCID: PMC8343944

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