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Article

Expanded Histologic Lineage and Origin of Mesonephric-Like Adenocarcinoma: A Clinicopathologic Study of 9 Cases.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 May 2026

Shi Yuxiang, Lyu Xiaojuan, Zheng Jing, Luo Bo, Li Li, Li Bin, Li Ruiting, Zhang Hongfeng

Abstract excerpt

Mesonephric-like adenocarcinoma (MLA) is a rare gynecologic malignancy primarily arising in the uterine corpus and ovaries. It shares remarkable similarities in its histomorphology, immunophenotype, and molecular features with mesonephric adenocarcinoma of the cervix. Controversy remains regarding whether the MLA originates from the mesonephric or Müllerian ducts. In this study, we retrospectively analyzed the...

Topics

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Adenocarcinoma
Aged
Immunohistochemistry
Mullerian Ducts
Ovarian Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins B-raf

Proto-Oncogene Proteins p21(ras)

PTEN Phosphohydrolase

Source

Identifiers

PMID: 41744277
DOI: 10.1097/PGP.0000000000001154

Genes

BRAF
ERBB3
KRAS
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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