Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ANGPTL3 gene variants in subjects with familial combined hyperlipidemia.

Scientific reports - 26 Mar 2021

Bea A M, Franco-Marín E, Marco-Benedí V, Jarauta E, Gracia-Rubio I, Cenarro A, Civeira F, Lamiquiz-Moneo I

Abstract excerpt

Angiopoietin-like 3 (ANGPTL3) plays an important role in lipid metabolism in humans. Loss-of-function variants in ANGPTL3 cause a monogenic disease named familial combined hypolipidemia. However, the potential contribution of ANGPTL3 gene in subjects with familial combined hyperlipidemia (FCHL) has not been studied. For that reason, the aim of this work was to investigate the potential contribution of ANGPTL3 in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Angiopoietin-Like Protein 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Angiopoietin-like Proteins

Share to Case-Control Studies

Share to Gain of Function Mutation

Share to Hyperlipidemia, Familial Combined

Share to Lipid Metabolism

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 33772079
DOI: 10.1038/s41598-021-86384-y
PMCID: PMC7997994

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ANGPTL3 gene variants in subjects with familial combined hyperlipidemia.PMID 33772079Read ↗

ANGPTL3 Gene Variants in Subjects With Familial Combined HyperlipidemiaSemantic proximity Read ↗

Exome Sequencing,<i>ANGPTL3</i>Mutations, and Familial Combined HypolipidemiaSemantic proximity Read ↗

Molecular mechanisms, prevalence, and molecular methods for familial combined hyperlipidemia disease: A reviewSemantic proximity Read ↗

Identification of a Gain-of-Function LIPC Variant as a Novel Cause of Familial Combined HypocholesterolemiaSemantic proximity Read ↗

Familial combined hyperlipidemia: An overview of the underlying molecular mechanisms and therapeutic strategiesSemantic proximity Read ↗

Genetics of familial combined hyperlipidemia.Semantic proximity Read ↗

Prevalence of ANGPTL3 and APOB gene mutations in subjects with combined hypolipidemia.Semantic proximity Read ↗

Clinical characteristics and plasma lipids in subjects with familial combined hypolipidemia: a pooled analysis.Semantic proximity Read ↗

Mutations in the ANGPTL3 gene and familial combined hypolipidemia: a clinical and biochemical characterization.Semantic proximity Read ↗

Unraveling the complex genetics of familial combined hyperlipidemia.Semantic proximity Read ↗

ANGPTL3 serum concentration and rare genetic variants in Finnish population.Semantic proximity Read ↗

Six years' experience with LipidSeq: clinical and research learnings from a hybrid, targeted sequencing panel for dyslipidemias.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.