Human leukocyte antigen (HLA) A-C-B-DRB1-DQB1 haplotype segregation analysis among 2152 families in China and the comparison to expectation-maximization algorithm result

Abstract excerpt

Human leukocyte antigen (HLA) is the major histocompatibility complex for humans. Previous studies have shown that high-resolution HLA matching can reduce graft vs. host disease and improve the outcome of hematopoietic stem cell transplantation (HSCT). Unrelated donor HSCT is very important when patients have no HLA-identical sibling donors. However, the chance of finding an available unrelated donor is not equal...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Hematopoietic Stem Cell Transplantation
• Share to Immune Cell Function and Interaction
• Share to T-cell and B-cell Immunology