Article
Pbp1 mediates the aberrant expression of genes involved in growth defect of ccr4∆ and pop2∆ mutants in yeast Saccharomyces cerevisiae.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Jun 2021
Valderrama Arvin Lapiz, Fujii Shiori, Duy Duong Long, Irie Kaoru, Mizuno Tomoaki, Suda Yasuyuki, Irie Kenji
Abstract excerpt
CCR4 and POP2 genes encode the catalytic subunit of the Ccr4-Not complex involved in shortening mRNA poly(A) tail in Saccharomyces cerevisiae. The ccr4Δ and pop2∆ mutants exhibit pleiotropic phenotypes such as slow and temperature-sensitive growth, aberrant expression of glucose repression genes and abnormal cell wall synthesis. We previously found that the growth defect of the ccr4Δ and pop2∆ mutants is...
Topics
- Carrier Proteins
- Cell Proliferation
- Environment
- Gene Deletion
- Gene Expression Regulation, Fungal
- Models, Biological
- Mutation
- Promoter Regions, Genetic
- RNA, Messenger
- Ribonucleases