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Article

Gene polymorphisms in leptin and its receptor and the response to growth hormone treatment in patients with idiopathic growth hormone deficiency.

Endocrine journal - 28 Aug 2021

Hwang Il Tae, Kim Mijin, Kim Nan Young, Yoon Jong Seo, Lee Hye Jin, Jeong Hwal Rim, Shim Young Suk, Kang Min Jae

Abstract excerpt

This study aimed to investigate the relationships between genetic polymorphisms of leptin/receptor genes and clinical/biochemical characteristics in children with growth hormone deficiency (GHD). Ninety-three GHD children and 69 age-matched normal controls were enrolled. Anthropometric measurements, bone age, and laboratory test results were obtained. Polymorphisms in the LEP gene promoter locus (LEP-2548,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 33762520
DOI: 10.1507/endocrj.EJ20-0788

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