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Article

Combinatorial Approaches to the Treatment of Advanced Melanoma.

Hematology/oncology clinics of North America - 1 Feb 2021

Munhoz Rodrigo Ramella, Postow Michael Andrew

Abstract excerpt

The treatment landscape for patients with advanced melanoma has dramatically improved over the past decade, leading to unprecedented survival. Despite the robust activity of single-agent immune-checkpoint blockade with anti-CTLA-4 or anti-PD-1 agents, and the efficacy of targeted therapies capable of interrupting aberrant signaling resulting from BRAF mutations, the benefit from these therapies is not universal....

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Share to Antineoplastic Agents, Immunological
Share to Drug Resistance, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Immune Checkpoint Inhibitors

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Share to Mitogen-Activated Protein Kinase Kinases

Share to Proto-Oncogene Proteins B-raf

Source

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Identifiers

PMID: 33759771
DOI: 10.1016/j.hoc.2020.08.015
PMCID: PMC9428831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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