Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Capsular polysaccharide switching in Streptococcus suis modulates host cell interactions and virulence.

Scientific reports - 22 Mar 2021

Okura Masatoshi, Auger Jean-Philippe, Shibahara Tomoyuki, Goyette-Desjardins Guillaume, Van Calsteren Marie-Rose, Maruyama Fumito, Kawai Mikihiko, Osaki Makoto, Segura Mariela, Gottschalk Marcelo, Takamatsu Daisuke

Abstract excerpt

The capsular polysaccharide (CPS) of Streptococcus suis defines various serotypes based on its composition and structure. Though serotype switching has been suggested to occur between S. suis strains, its impact on pathogenicity and virulence remains unknown. Herein, we experimentally generated S. suis serotype-switched mutants from a serotype 2 strain that express the serotype 3, 4, 7, 8, 9, or 14 CPS. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Capsules
Share to Dendritic Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial Cells

Share to Host-Pathogen Interactions

Share to Macrophages

Share to Serogroup

Share to Streptococcus suis

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 33753801
DOI: 10.1038/s41598-021-85882-3
PMCID: PMC7985379

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Capsular polysaccharide switching in Streptococcus suis modulates host cell interactions and virulence.PMID 33753801Read ↗

Capsular polysaccharide switching in <i>Streptococcus suis</i> modulates host cell interactions and virulenceSemantic proximity Read ↗

Role of the Streptococcus suis serotype 2 capsular polysaccharide in the interactions with dendritic cells is strain-dependent but remains critical for virulenceSemantic proximity Read ↗

Comparative genetic analyses provide clues about capsule switching in Streptococcus suis 2 strains with different virulence levels and genetic backgroundsSemantic proximity Read ↗

Serotype-specific role of antigen I/II in the initial steps of the pathogenesis of the infection caused by Streptococcus suisSemantic proximity Read ↗

Surface-associated and secreted factors of<i>Streptococcus suis</i>in epidemiology, pathogenesis and vaccine developmentSemantic proximity Read ↗

Serotype switching in <i>Pseudomonas aeruginosa</i> ST111 enhances adhesion and virulenceSemantic proximity Read ↗

A single amino acid polymorphism in the glycosyltransferase CpsK defines four Streptococcus suis serotypes.Semantic proximity Read ↗

PrsA contributes to Streptococcus suis serotype 2 pathogenicity by modulating secretion of selected virulence factorsSemantic proximity Read ↗

Type I Interferon Induced by Streptococcus suis Serotype 2 is Strain-Dependent and May Be Beneficial for Host SurvivalSemantic proximity Read ↗

Changes in capsular serotype alter the surface exposure of pneumococcal adhesins and impact virulence.Semantic proximity Read ↗

A capsular polysaccharide-expressing live vaccine suppresses streptococcal toxic shock-like syndrome and provides sequence type-independent protection during <i>Streptococcus suis</i> infectionSemantic proximity Read ↗

Serotype-Dependent Effects on the Dynamics of Pneumococcal Colonization and Implications for TransmissionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.