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Reconstructing unseen transmission events to infer dengue dynamics from viral sequences

22 Mar 2021

Abstract excerpt

For most pathogens, transmission is driven by interactions between the behaviours of infectious individuals, the behaviours of the wider population, the local environment, and immunity. Phylogeographic approaches are currently unable to disentangle the relative effects of these competing factors. We develop a spatiotemporally structured phylogenetic framework that addresses these limitations by considering...

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PMID: 33753725
DOI: 10.1038/s41467-021-21888-9

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