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Article

Off-the-Shelf Chimeric Antigen Receptor T Cells

1 Mar 2021

Abstract excerpt

ABSTRACT: Banked chimeric antigen receptor (CAR) T cells immediately available for off-the-shelf (OTS) application can solve key limitations of patient-specific CAR T-cell products while retaining their potency. The allogeneic nature of OTS cell therapies requires additional measures to minimize graft-versus-host disease and host-versus-graft immune rejection in immunocompetent recipients. In this review, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33750078
DOI: 10.1097/ppo.0000000000000511

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