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Article

Effect of CYP2C19 Genotype on Ischemic Outcomes During Oral P2Y12 Inhibitor Therapy: A Meta-Analysis.

JACC. Cardiovascular interventions - 12 Apr 2021

Pereira Naveen L, Rihal Charanjit, Lennon Ryan, Marcus Gil, Shrivastava Sanskriti, Bell Malcolm R, So Derek, Geller Nancy, Goodman Shaun G, Hasan Ahmed, Lerman Amir, Rosenberg Yves, Bailey Kent, Murad M Hassan, Farkouh Michael E

Abstract excerpt

OBJECTIVES: The aim of this study was to examine the effect of CYP2C19 genotype on clinical outcomes in patients with coronary artery disease (CAD) who predominantly underwent percutaneous coronary intervention (PCI), comparing those treated with ticagrelor or prasugrel versus clopidogrel. BACKGROUND: The effect of CYP2C19 genotype on treatment outcomes with ticagrelor or prasugrel compared with clopidogrel is...

Topics

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Antiplatelet Therapy and Cardiovascular Diseases
Cytochrome P-450 CYP2C19
Eicosanoids and Hypertension Pharmacology
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Myocardial Infarction

Platelet Aggregation Inhibitors

Treatment Outcome

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Identifiers

PMID: 33744207
DOI: 10.1016/j.jcin.2021.01.024
PMCID: PMC9853943

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