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Article

The structure of a major surface antigen SAG19 from Eimeria tenella unifies the Eimeria SAG family.

Communications biology - 19 Mar 2021

Ramly Nur Zazarina, Dix Samuel R, Ruzheinikov Sergey N, Sedelnikova Svetlana E, Baker Patrick J, Chow Yock-Ping, Tomley Fiona M, Blake Damer P, Wan Kiew-Lian, Nathan Sheila, Rice David W

Abstract excerpt

In infections by apicomplexan parasites including Plasmodium, Toxoplasma gondii, and Eimeria, host interactions are mediated by proteins including families of membrane-anchored cysteine-rich surface antigens (SAGs) and SAG-related sequences (SRS). Eimeria tenella causes caecal coccidiosis in chickens and has a SAG family with over 80 members making up 1% of the proteome. We have solved the structure of a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33742128
DOI: 10.1038/s42003-021-01904-w
PMCID: PMC7979774

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